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赵宁宁 讲师

赵宁宁,2025年6月毕业于山东师范大学,获得分析化学专业博士学位。近年来在 Chemical Engineering Journal、 Analytical Chemistry、Biosensors and Bioelectronics、Sensors and Actuators B: Chemical等期刊以第一作者或通讯作者发表 SCI 论文11 篇。

研究方向

1. 核酸修复酶的灵敏检测研究

2. 表观遗传生物标志物的灵敏检测研究

3. 单分子荧光生物传感器的构建及其临床应用研究

发表论文

1. Ning-ning Zhao, Qian Wang, Hao Liu, Meng Liu, Qinfeng Xu, Huimin Yuan, Chun-yang Zhang*. Construction of a N6-methyladenosine demethylation-switched deoxyribozyme circuit for in vitro and in situ detection of FTO activity. Chemical Engineering Journal, 2024, 493: 152840.

2. Ning-ning Zhao, Fang-yu Guo, Bao-mei Zhou, Meng Liu*, Chun-yang Zhang*. Construction of a multiple cyclic ligation-promoted exponential recombinase polymerase amplification platform for sensitive and simultaneous monitoring of cancer biomarkers Fpg and FEN1. Analytical Chemistry, 2024, 97(5): 3099-3107.

3. Ning-ning Zhao, Qian Wang, Dong-ming Yang, Dong-ling Li, Yun Han, Shulin Zhao*, Xiaoran Zou*, Chun-yang Zhang*. Elongation and ligation-mediated differential coding for label-free and locus-specific analysis of 8-Oxo-7,8-dihydroguanine in DNA. Analytical Chemistry, 2024, 96(13): 5323-5330.

4. Ning-ning Zhao, Ya-zhen Liu, Lingfei Zhang, Wenjing Liu, Xiaoran Zou*, Qinfeng Xu*, Chun-yang Zhang*. Construction of multiple DNAzymes driven by single base elongation and ligation for single-molecule monitoring of FTO in cancer tissues. Analytical Chemistry, 2023, 95(34): 12974-12981.

5. Ning-Ning Zhao, Xiao-Di Yu, Xiaorui Tian, Qinfeng Xu*, Chun-Yang Zhang*. Mix-and-detection assay with multiple cyclic enzymatic repairing amplification for rapid and ultrasensitive detection of long noncoding RNAs in breast tissues. Analytical Chemistry, 2023, 95(5): 3082-3088.

6. Ning-ning Zhao, Xinyi Zhang, Xiaoran Zou, Yan Zhang*, Chun-yang Zhang*. Controllable assembly of dendritic DNA nanostructures for ultrasensitive detection of METTL3-METTL14 m6A methyltransferase activity in cancer cells and human breast tissues. Biosensors and Bioelectronics, 2023, 228: 115217.

7. Ning-ning Zhao, Xiaorui Tian, Fei Ma*, Chun-yang Zhang*. CRISPR/Cas12a-enhanced single-molecule counting for sensitive detection of flap endonuclease 1 activity at the single-cell level. Chemical Communications, 2023, 59(33): 4939-4942.

8. Ning-ning Zhao, Wen-jing Liu, Xiaorui Tian, Baogang Zhang*, Chun-yang Zhang*. Target-activated cascade transcription amplification lights up RNA aptamers for label-free detection of metalloproteinase-2 activity. Chemical Communications, 2023, 59(8):1058-1061.

9. Meng Liu, Wen Zhang, Chen-Chen Li, Dandan Zhang, Ning-Ning Zhao*, Chun-Yang Zhang*. Construction of a bifunctional single-quantum dot nanosensor for enzyme-free detection of N6-methyladenosine demethylase in breast cancer. Analytical Chemistry, 2025, 97(44):24625-24633

10. Dandan Zhang, Xiangyue Cai, Ting Luo, Ning-ning Zhao*, Chun-yang Zhang*. Construction of a fluorescent and colorimetric multi-mode aptasensor for label-free and sensitive detection of ochratoxin A in agricultural products. Sensors and Actuators B: Chemical, 2024, 410:135677.

11. Dandan Zhang, Ting Luo, Xiangyue Cai, Ning-Ning Zhao*, Chun-yang Zhang*. Recent advances in nucleic acid signal amplification-based aptasensors for sensing mycotoxins. Chemical Communications, 2024, 60(36):4745-4764.

奖励

1. 2024.12 获博士研究生国家奖学金;

2. 2024.12 获第五届济南奖学金;

3. 2024.11 获第三届中国研究生“双碳”创新与创意大赛二等奖;

4. 2024.10 获第十一届中国研究生能源装备创新设计大赛三等奖。

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