基本信息：姜苏，讲师，分析化学博士，2024年6月毕业于山东师范大学。主要从事构建基于荧光或单分子检测的生物传感策略。目前以第一作者或共同第一作者身份在Nano Lett.,Anal. Chem.,Biosens.Bioelectron.,Sens. Actuators B Chem., Chem. Commun.等期刊发表SCI论文26篇。
研究方向
1开发基于有机染料的非标记检测方法
2单分子/荧光检测及其临床应用研究
发表论文
1Jiang, S.; Cai, Y. B.; Zhang, Q. Y.; Liu, Q.; Wang, Z. Y.; Zhang, C. Y. Bioorthogonal reaction-mediated enzymatic elongation-driven dendritic nanoassembly for genome-wide analysis of 5-hydroxymethyluracil in breast tissues.Nano Lett.2023, 23, 10625-10632.
2.Jiang, S.; Shi, H. H.; Zhang, Q.; Wang, Z. Y.; Zhang, Y.; Zhang, C. Y. Rolling circle transcription amplification-directed construction of tandem spinach-based fluorescent light-up biosensor for label-free sensing ofβ-glucosyltransferase activity.Biosens. Bioelectron.2023, 237, 115513.
3.Jiang, S.; Liu, T.; Liu, Q.; Zhang, Q.; Han, Y.; Tian, X. R.; Zhang, C. Y. Rapid, sensitive, and label-free detection of long noncoding RNAs in breast cancer tissues by RecJfexonuclease-assisted recombinase polymerase amplification.Anal. Chem.2023, 95, 15133-15139.
4.Jiang, S.; Ren, J. Y.; Zhang, Q.; Liu, W. J.; Liu, H.; Xu, Q. F.; Tian, X. R.; Zhang, C. Y. Construction of a dendritic nanoassembly-based fluorescent biosensor for electrostatic interaction-independent and label-free measurement of human poly(ADP-ribose) polymerase 1 in lung tissues.Anal. Chem.2023, 95, 11815-11822.
5.Jiang, S.; Liu, Q.; Hu, J.; Yuan, D.; Zhang, Y.; Zhang, C. Y. Target-triggered assembly of functional G-quadruplex DNAzyme nanowires for sensitive detection of miRNA in lung tissues.Sens. Actuators B Chem.2022, 373, 132689.
6.Jiang, S.; Liu, Q.; Liu, W. J.; Cui, L.; Zhang, C. Y. Label-free detection of lncRNA in cancer cells with human telomere G-quadruplex DNA-thioflavin t binding-induced fluorescence.Sens. Actuators B Chem.2022, 358, 131521.
7.Jiang, S.; Liu, M.; Wei, T. T.; Xu, Q. F.; Zou, X. R.; Ma, F.; Zhang, C. Y. Aptamer-mediated rolling circle amplification for label-free and sensitive detection of histone acetyltransferase activity.Chem. Commun.2021, 57, 2041-2044.
8.Jiang, S.; Ren, J. Y.; Xu, Q. F.; Zou, X. R.; Li, Y. Y.; Zhang, C. Y. Simultaneous single-molecule detection of the acetyltransferase and crotonyltransferase activities of histone acetylation writer p300.Chem. Commun.2021, 57, 11709-11712.
专利
siRNA定向自组装量子点生物传感器及其检测方法和应用
奖励
1.获第六届全国大学生制药工程设计比赛全国二等奖；
2.获山东省优秀毕业生；
3.获山东省大学生科技创新大赛一等奖两次/二等奖一次；
4.获山东省研究生优秀成果奖二等奖一次/三等奖一次。
